Description

2-Fluoro-3-(Methylsulphonyl)Anisole is a high-value fluorinated aromatic building block characterized by its unique combination of fluorine, methoxy, and methylsulfonyl substituents. This compound is critical for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals where its specific substitution pattern can modulate biological activity and physicochemical properties. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of potential drug candidates, especially in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, where the fluorine atom enhances bioavailability and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science: Employed in the synthesis of advanced polymers and liquid crystals, where the sulfone and ether groups contribute to thermal stability and specific electronic properties.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags or molecular probes to study biological pathways.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2-Fluoro-3-(Methylsulphonyl)Anisole
CAS No.	942474-33-1
Molecular Formula	C8H9FO3S
Molecular Weight	204.22 g/mol
Synonyms	1-Fluoro-2-Methoxy-3-(Methylsulfonyl)Benzene; 3-(Methylsulfonyl)-2-Fluoroanisole; 2-Fluoro-3-Methanesulfonylanisole; Benzene, 1-fluoro-2-methoxy-3-(methylsulfonyl)-; 2-Fluoroanisole-3-methyl sulfone
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-3-(Methylsulphonyl)Anisole is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, and custom specifications can be developed to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.