Description

8-Chloro-1,4-Dihydro-4-Oxo-3-Quinolinecarboxylic Acid Methyl Ester is a high-purity, synthetically valuable quinoline derivative. This compound serves as a critical advanced intermediate in the development of novel active pharmaceutical ingredients (APIs), particularly within the fluoroquinolone antibiotic class. It is essential for research and production facilities in the pharmaceutical, agrochemical, and fine chemical sectors seeking reliable, high-quality building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of next-generation fluoroquinolone antibiotics and other biologically active quinoline-based molecules.
• Organic Synthesis Building Block: Used in research and development for constructing complex heterocyclic compounds due to its reactive ester and chloro substituents.
• Agrochemical Research: Employed in the discovery and development of new crop protection agents and pesticides.
• Material Science Research: Investigated for potential applications in creating organic electronic materials or functional dyes.
• Academic & Contract Research: Serves as a standard or starting material in university laboratories and CROs (Contract Research Organizations) for medicinal chemistry programs.

Basic Information

Product Name	8-Chloro-1,4-Dihydro-4-Oxo-3-Quinolinecarboxylic Acid Methyl Ester
CAS No.	942227-33-0
Molecular Formula	C12H8ClNO3
Molecular Weight	249.65 g/mol
Synonyms	Methyl 8-chloro-1,4-dihydro-4-oxoquinoline-3-carboxylate; 8-Chloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid methyl ester; 8-Chloro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid methyl ester; 3-Quinolinecarboxylic acid, 8-chloro-1,4-dihydro-4-oxo-, methyl ester; CAS 942227-33-0
EINECS	Contact for details

Quality Control

Our 8-Chloro-1,4-Dihydro-4-Oxo-3-Quinolinecarboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets precise customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.