Description

Methyl-3-(3,5-Difluorophenoxy)Acrylate CAS NO 942195-89-3 is a high-purity, fluorinated acrylate ester building block of significant importance in advanced organic synthesis. Its core value lies in its unique molecular structure, which incorporates both a reactive acrylate moiety and a difluorophenoxy group, making it a versatile intermediate for constructing complex molecules. This compound is primarily needed by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored surface properties, such as low surface energy coatings.
• Liquid Crystal & OLED Materials: Intermediate for synthesizing fluorinated components used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Chemical Biology Probe Development: Utilized in medicinal chemistry for creating fluorescent tags or activity-based probes to study biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring fluorinated acrylate chemistry.

Basic Information

Product Name	Methyl-3-(3,5-Difluorophenoxy)Acrylate
CAS No.	942195-89-3
Molecular Formula	C10H8F2O3
Molecular Weight	214.17 g/mol
Synonyms	Methyl (2E)-3-(3,5-difluorophenoxy)acrylate; (E)-Methyl 3-(3,5-difluorophenoxy)acrylate; Methyl trans-3-(3,5-difluorophenoxy)acrylate; 3,5-Difluorophenoxy acrylic acid methyl ester; Methyl 3-(3,5-difluorophenoxy)-2-propenoate; 2-Propenoic acid, 3-(3,5-difluorophenoxy)-, methyl ester, (2E)-
EINECS	Contact for details

Quality Control

Our Methyl-3-(3,5-Difluorophenoxy)Acrylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets exacting standards for research and scale-up applications. Certificates of Analysis (COA) with complete batch data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Isomeric Purity (E/Z Ratio)	≥ 95:5 (E:Z)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.