Description

(R)-3-(4-Benzylphenoxy)Pyrrolidine Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant interest in modern organic synthesis. Its value lies in its defined stereochemistry and functionalized pyrrolidine core, which are crucial for developing active pharmaceutical ingredients (APIs) with specific biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and process development of new therapeutic agents, particularly in neurological and cardiovascular research.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, especially for central nervous system (CNS) targets.
• Asymmetric Synthesis: Used as a building block for constructing complex molecules with high enantiomeric purity in medicinal chemistry.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in stereoselective transformations.
• Chemical Biology Research: Employed in the design and synthesis of molecular probes to study biological pathways and protein interactions.
• Process Chemistry: Utilized in scaling up synthetic routes for potential APIs during late-stage development and optimization.

Basic Information

Product Name	(R)-3-(4-Benzylphenoxy)Pyrrolidine Hydrochloride
CAS No.	942194-85-6
Molecular Formula	C17H20ClNO
Molecular Weight	289.80 g/mol
Synonyms	(R)-3-(4-Benzylphenoxy)pyrrolidine HCl; (3R)-3-(4-Benzylphenoxy)pyrrolidine hydrochloride; Pyrrolidine, 3-(4-benzylphenoxy)-, hydrochloride, (3R)-; (R)-3-(p-Benzylphenoxy)pyrrolidine hydrochloride; (R)-1-(4-Benzylphenoxy)-3-pyrrolidinol hydrochloride (tautomeric form); UNII-8F8P678Q0H; 942194-85-6; Benzylphenoxypyrrolidine hydrochloride (R-enantiomer)
EINECS	Contact for details

Quality Control

Our (R)-3-(4-Benzylphenoxy)Pyrrolidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.