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((R)-1-Diphenylphosphino-2-[(R)-A-(N,n-Dimethylamino)-o-Diphenylphosphinophenyl)Methyl]Ferrocene)- (N5-2,4-Dimethylpentadienyl)-Ruthenium-Iodide CAS NO 942042-52-6


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CAS No.:942042-52-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

((R)-1-Diphenylphosphino-2-[(R)-A-(N,n-Dimethylamino)-o-Diphenylphosphinophenyl)Methyl]Ferrocene)- (N5-2,4-Dimethylpentadienyl)-Ruthenium-Iodide is a highly specialized, chiral organometallic complex designed for advanced asymmetric catalysis. This compound matters because it serves as a precise and efficient catalyst for critical carbon-carbon and carbon-heteroatom bond-forming reactions, enabling the synthesis of enantiomerically pure pharmaceutical intermediates and fine chemicals. It is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require high stereoselectivity and yield.

Application

  • Asymmetric Hydrogenation: A key catalyst for the enantioselective reduction of prochiral olefins, ketones, and imines to produce chiral alcohols and amines.
  • Pharmaceutical Intermediate Synthesis: Enables the production of single-enantiomer active pharmaceutical ingredients (APIs) for drugs targeting CNS disorders, cardiovascular diseases, and infectious diseases.
  • Agrochemical Manufacturing: Used in the synthesis of chiral herbicides, fungicides, and pesticides with improved efficacy and environmental profile.
  • Asymmetric C-C Bond Formation: Facilitates reactions like asymmetric allylic alkylation and hydroformylation for constructing complex molecular architectures.
  • Fine Chemical and Fragrance Production: Applied in the creation of high-value chiral flavor and fragrance compounds.
  • Academic and Industrial R&D: Serves as a valuable tool for methodological development in organic synthesis and catalysis research.
  • Material Science Precursor: Potential use in the development of chiral metal-organic frameworks (MOFs) or polymeric materials.

Basic Information

Item Details
Product Name ((R)-1-Diphenylphosphino-2-[(R)-A-(N,n-Dimethylamino)-o-Diphenylphosphinophenyl)Methyl]Ferrocene)- (N5-2,4-Dimethylpentadienyl)-Ruthenium-Iodide
CAS No. 942042-52-6
Molecular Formula Contact for details
Molecular Weight Contact for details
Synonyms Ru-JOSIPHOS type complex; Ruthenium JOSIPHOS catalyst; (R)-JOSIPHOS-Ru(diene) iodide; Chiral ruthenium diphosphine complex; Asymmetric hydrogenation ruthenium catalyst; [Ru((R)-JOSIPHOS)(2,4-dimethylpentadienyl)]I; Ruthenium(I) (η5-2,4-dimethylpentadienyl)((R)-1-((S)-2-(diphenylphosphino)ferrocenyl)ethyldi(3,5-xylyl)phosphine) iodide
EINECS Contact for details

Quality Control

Every batch of our chiral ruthenium catalyst is produced and tested under strict quality management protocols to ensure exceptional purity and catalytic performance. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as chiral purity, metal content, and spectroscopic identity. Our quality systems support development under cGMP and ISO 9001 guidelines, ensuring traceability and consistency for critical pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a dry, cold environment. This compound is moisture-sensitive and easily oxidized; prolonged exposure to air, light, or ambient temperature will degrade its catalytic activity. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item Specification
Appearance Orange to red-brown solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 95%
Chiral Purity (Chiral HPLC) ≥ 99% ee
Ruthenium Content (ICP-OES) Contact for details
Solubility Soluble in common organic solvents (DCM, THF, Toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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