Description

2-Chloro-N-(3-fluorophenyl)propanamide is a specialized halogenated aromatic amide building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique chloro-fluoro substitution pattern enables precise molecular modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of next-generation herbicides and fungicides, leveraging its halogenated structure for enhanced bioactivity.
• Chemical Biology Probe Synthesis: Employed in the creation of molecular probes for studying enzyme function and protein-ligand interactions.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the research of specialty polymers with specific thermal or optical properties.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Chloro-N-(3-fluorophenyl)propanamide
CAS No.	941400-35-7
Molecular Formula	C9H9ClFNO
Molecular Weight	201.63 g/mol
Synonyms	2-Chloro-N-(3-fluorophenyl)propanamide; Propanamide, 2-chloro-N-(3-fluorophenyl)-; N-(3-Fluorophenyl)-2-chloropropanamide; 3-Fluoro-α-chloropropionanilide; 2-Chloro-N-(3-fluorophenyl)propionamide; α-Chloro-3-fluoropropionanilide; 941400-35-7; 2-Chloro-N-(m-fluorophenyl)propanamide
EINECS	Contact for details

Quality Control

Our 2-Chloro-N-(3-fluorophenyl)propanamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity determination and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.