Description

Boc-L-4-Nitrophe CAS NO 33305-77-0 is a high-purity, protected amino acid derivative widely used as a critical building block in peptide synthesis. Its primary value lies in enabling the controlled introduction of the 4-nitrophenylalanine residue into peptide chains, which is essential for research into enzyme inhibitors and bioactive peptides. This compound is particularly vital for pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel therapeutic agents and advanced biomaterials.

Application

• Peptide Synthesis: A key intermediate for the solid-phase and solution-phase synthesis of complex peptides.
• Pharmaceutical Research: Used in the development of enzyme inhibitors, receptor agonists/antagonists, and other bioactive peptide-based drug candidates.
• Bioconjugation: Serves as a precursor for creating labeled peptides or peptide-protein conjugates for diagnostic and research purposes.
• Chemical Biology Probes: Employed in the synthesis of peptides designed to study protein-protein interactions and cellular signaling pathways.
• Academic Research: A fundamental reagent in university and institutional labs for studying peptide structure-activity relationships.
• Fine Chemical Production: An important building block for custom synthesis services and the manufacture of specialized non-peptide compounds containing aromatic nitro groups.

Basic Information

Product Name	Boc-L-4-Nitrophe CAS NO 33305-77-0
CAS No.	33305-77-0
Molecular Formula	C14H18N2O6
Molecular Weight	310.31 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-4-nitro-L-phenylalanine; Boc-4-NO2-Phe-OH; Boc-L-4-Nitrophenylalanine; (2S)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-3-(4-nitrophenyl)propanoic acid; N-Boc-4-nitro-L-phenylalanine; tert-Butyloxycarbonyl-4-nitro-L-phenylalanine; Boc-Phe(4-NO2)-OH; Boc-L-Phe(4-NO2)
EINECS	Contact for details

Quality Control

Our Boc-L-4-Nitrophe is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, typically meeting standards suitable for pharmaceutical research. Each lot undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity. Certificates of Analysis (COA) detailing specific results for identity, assay, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant in the storage area.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	Specific range available on COA
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	<10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.