Description

3-Bromo-5-Chloro-4-Methylbenzonitrile is a high-purity halogenated benzonitrile derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its unique substitution pattern, which provides a versatile and reactive scaffold for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where its halogenated aromatic core contributes to biological activity.
• Material Science Research: Acts as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials due to its rigid, substituted benzene ring.
• Chemical Synthesis: Serves as a versatile electrophile in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic aromatic substitution for introducing functional complexity.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments where the nitrile and halogen groups modify color and stability properties.

Basic Information

Product Name	3-Bromo-5-Chloro-4-Methylbenzonitrile
CAS No.	939990-02-0
Molecular Formula	C8H5BrClN
Molecular Weight	230.49 g/mol
Synonyms	3-Bromo-5-chloro-p-tolunitrile; 4-Methyl-3-bromo-5-chlorobenzonitrile; 2-Bromo-6-chloro-4-cyanotoluene; Benzonitrile, 3-bromo-5-chloro-4-methyl-; 3-Bromo-5-chloro-4-methylbenzenecarbonitrile; 5-Chloro-3-bromo-4-methylbenzonitrile
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our chemical intermediates. Production of 3-Bromo-5-Chloro-4-Methylbenzonitrile is monitored through in-process controls and final batch analysis using advanced techniques like HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, ensuring full traceability and compliance with your research or manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.