Description

3-(3-Nitro-Pyridin-2-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate with a molecular formula of C15H22N4O4 and a molecular weight of 322.36. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and novel chemical entities, offering a key building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and fine chemical producers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile building block for constructing novel heterocyclic scaffolds and exploring structure-activity relationships (SAR) in drug discovery programs.
• API Development: Used in the process development and scale-up stages for the production of target active pharmaceutical ingredients.
• Chemical Biology Probes: Employed in the synthesis of specialized molecules used to study biological pathways and protein functions.
• Custom Synthesis: A starting material for contract synthesis services producing bespoke compounds for client-specific research needs.
• Academic Research: Utilized in university and institutional laboratories for synthetic organic chemistry and pharmaceutical sciences projects.

Basic Information

Item	Details
Product Name	3-(3-Nitro-Pyridin-2-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	939986-16-0
Molecular Formula	C15H22N4O4
Molecular Weight	322.36 g/mol
Synonyms	tert-Butyl 3-[(3-nitropyridin-2-yl)amino]piperidine-1-carboxylate; 1-Boc-3-[(3-nitro-2-pyridinyl)amino]piperidine; 1-(tert-Butoxycarbonyl)-3-[(3-nitropyridin-2-yl)amino]piperidine; 3-[(3-Nitro-2-pyridinyl)amino]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; N-(3-Nitropyridin-2-yl)-1-Boc-piperidin-3-amine; Boc-Pip(3-NH-3-NO2-Py)-OH tert-butyl ester; 939986-16-0; 3-(3-Nitro-pyridin-2-ylamino)-piperidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 3-(3-Nitro-Pyridin-2-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under a quality management system and undergoes rigorous analytical testing to ensure batch-to-batch consistency and high purity. Each lot is supplied with a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Our standard 98+% purity grade is confirmed by HPLC, with specifications tailored to meet the stringent requirements of pharmaceutical R&D and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and desiccated to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to light brown solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.