Description

3-(3-Chloro-Quinoxalin-2-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate with a molecular formula of C18H23ClN4O2 and a molecular weight of 362.86. This compound is critical for medicinal chemistry research and development, serving as a key building block in the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new drug candidates, particularly in the areas of kinase inhibitors and other targeted small molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of complex active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a scaffold or building block for constructing novel chemical libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Kinase Inhibitor Development: The quinoxaline core structure makes it valuable for research into potential kinase inhibitors for oncology and inflammatory diseases.
• Process Chemistry & Scale-Up: Serves as a key material for process optimization and pilot-scale production of candidate drugs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.
• Academic Research: Used in university and institutional labs for exploratory research in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	3-(3-Chloro-Quinoxalin-2-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	939986-04-6
Molecular Formula	C18H23ClN4O2
Molecular Weight	362.86 g/mol
Synonyms	tert-Butyl 3-[(3-chloroquinoxalin-2-yl)amino]piperidine-1-carboxylate; 1-Boc-3-[(3-chloroquinoxalin-2-yl)amino]piperidine; 3-[(3-Chloro-2-quinoxalinyl)amino]-1-piperidinecarboxylic Acid 1,1-Dimethylethyl Ester; 3-(3-Chloroquinoxalin-2-ylamino)piperidine-1-carboxylic acid tert-butyl ester; 939986-04-6; BOC-3-(3-Chloroquinoxalin-2-Ylamino)piperidine
EINECS	Contact for details

Quality Control

Our 3-(3-Chloro-Quinoxalin-2-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality control protocols to ensure a purity of 98+%, meeting the stringent requirements of pharmaceutical R&D. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality system is designed to support regulatory filings, and we can provide material suitable for use under cGMP guidelines for non-clinical development stages upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	98.0% min
Water Content (KF)	1.0% max
Residue on Ignition	0.1% max
Heavy Metals	20 ppm max
Single Unknown Impurity (HPLC)	0.5% max
Total Impurities (HPLC)	2.0% max

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.