Description

4-(Cbz-Amino)-4'-Formylbiphenyl is a high-purity, bifunctional organic building block featuring both a carboxybenzyl (Cbz)-protected amine and an aldehyde group. This compound matters for its versatility as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and advanced material science. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active compounds and functional polymers.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Ligand Synthesis: Used to create sophisticated ligands for catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Serves as a monomer or cross-linking agent for producing specialty polymers with specific functional properties.
• Peptide Mimetics: Employed in the design and synthesis of peptidomimetics and other bioactive scaffolds.
• Liquid Crystal & OLED Materials: Acts as a core building block for advanced organic electronic materials due to its rigid biphenyl structure and formyl group.
• Chemical Biology Probes: Utilized in the development of probes and tags for studying biological processes.

Basic Information

Product Name	4-(Cbz-Amino)-4'-Formylbiphenyl
CAS No.	939758-25-5
Molecular Formula	C21H17NO3
Molecular Weight	331.37 g/mol
Synonyms	4'-Formyl-4-[(phenylmethoxy)carbonylamino]biphenyl; 4-[(Benzyloxycarbonyl)amino]-4'-formyl-1,1'-biphenyl; N-Cbz-4-Amino-4'-formylbiphenyl; 4-(N-Cbz-amino)biphenyl-4'-carboxaldehyde; 4-Amino-4'-formylbiphenyl Cbz derivative; Biphenyl-4,4'-dicarboxaldehyde mono-Cbz derivative
EINECS	Contact for details

Quality Control

Every batch of 4-(Cbz-Amino)-4'-Formylbiphenyl is produced and tested under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, NMR, and mass spectrometry, to ensure compliance with high-purity standards for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term stability. Keep container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.