Description

3,3-Difluorocyclopentanamine Hydrochloride, 98% is a high-purity, fluorinated amine salt of significant interest in advanced organic synthesis. This compound serves as a critical building block for the development of novel pharmaceutical candidates and agrochemicals, where the introduction of fluorine atoms can dramatically alter biological activity and metabolic stability. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, metabolic diseases, and anti-infectives.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, where the difluorocyclopentane moiety can enhance potency and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for chiral amines and ligands used in asymmetric catalysis, enabling the synthesis of enantiomerically pure compounds.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced materials where fluorinated cyclic structures impart unique thermal and chemical resistance properties.
• Chemical Biology Probe: Utilized as a scaffold for developing molecular probes to study enzyme function and biological pathways.

Basic Information

Product Name	3,3-Difluorocyclopentanamine Hydrochloride, 98%
CAS No.	939398-48-8
Molecular Formula	C5H10ClF2N
Molecular Weight	157.59 g/mol
Synonyms	3,3-Difluorocyclopentanamine HCl; 3,3-Difluorocyclopentylamine Hydrochloride; 3,3-Difluorocyclopentan-1-amine hydrochloride; 1-Amino-3,3-difluorocyclopentane hydrochloride; Cyclopentanamine, 3,3-difluoro-, hydrochloride (1:1); 939398-48-8; 3,3-Difluorocyclopentylammonium chloride
EINECS	Contact for details

Quality Control

Our 3,3-Difluorocyclopentanamine Hydrochloride is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and Karl Fischer titration, to ensure it meets the specified 98% purity and consistent quality. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.