Description

Benzyl 3,3-Difluorocyclopentylcarbamate is a specialized fluorinated carbamate building block of significant interest in advanced organic synthesis. Its molecular structure, featuring a difluorocyclopentyl moiety, makes it a valuable intermediate for constructing complex molecules with tailored physicochemical properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, metabolic diseases, and inflammation.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the difluorocyclopentyl group can enhance bioavailability and metabolic stability.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization programs due to its modifiable carbamate and fluorinated ring structure.
• Chemical Biology Probe Synthesis: Employed in the creation of molecular probes and labeled compounds for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds at various scales, from research to pilot plant.

Basic Information

Product Name	Benzyl 3,3-Difluorocyclopentylcarbamate
CAS No.	939385-02-1
Molecular Formula	C13H15F2NO2
Molecular Weight	255.26 g/mol
Synonyms	Carbamic acid, N-(3,3-difluorocyclopentyl)-, phenylmethyl ester; Benzyl N-(3,3-difluorocyclopentyl)carbamate; 3,3-Difluorocyclopentylcarbamic acid benzyl ester; (3,3-Difluorocyclopentyl)carbamic Acid Benzyl Ester; Bn-3,3-Difluorocyclopentylcarbamate; Benzyl (3,3-difluorocyclopentyl)carbamate
EINECS	Contact for details

Quality Control

Our Benzyl 3,3-Difluorocyclopentylcarbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development projects with custom purity grades, from research (e.g., >95%) to development (>98%) standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Research Grade)
Purity (HPLC)	≥ 98.0% (Development Grade)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.