Description

2-Chloro-8-Fluoroquinoline-3-Carbaldehyde is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogenated quinoline scaffold enables precise molecular modifications. It is primarily sought after by research and development chemists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules with targeted biological or functional properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for antimicrobial, anticancer, and central nervous system (CNS) agents.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and insecticides by leveraging the bioactive quinoline core.
• Material Science: Serves as a building block for creating specialized organic ligands, dyes, and photoactive materials.
• Chemical Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as an aldehyde component in condensation reactions to form new C-C and C-N bonds.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the discovery of new chemical entities.

Basic Information

Product Name	2-Chloro-8-Fluoroquinoline-3-Carbaldehyde
CAS No.	938138-88-6
Molecular Formula	C10H5ClFNO
Molecular Weight	209.60 g/mol
Synonyms	8-Fluoro-2-chloroquinoline-3-carboxaldehyde; 3-Formyl-2-chloro-8-fluoroquinoline; 2-Chloro-8-fluoroquinoline-3-carboxaldehyde; 2-Chloro-8-fluoro-3-quinolinecarboxaldehyde; Quinoline-3-carboxaldehyde, 2-chloro-8-fluoro-; 938138-88-6
EINECS	Contact for details

Quality Control

Our 2-Chloro-8-Fluoroquinoline-3-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring high-purity intermediates for research and scale-up.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere if long-term storage is required to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.