Description

n-(1-Phenylethyl)-1,4-Dioxaspiro[4.5]Decan-8-Amine is a specialized chiral amine derivative featuring a spirocyclic acetal-protected ketone moiety, which is a valuable synthetic intermediate in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of pharmaceuticals and fine chemicals where precise stereochemistry is critical. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring chiral amine centers.
• Asymmetric Catalyst Ligand Precursor: Used in the development and synthesis of novel chiral ligands for transition metal catalysis.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the discovery of new drug candidates.
• Fine Chemical Synthesis: Intermediate for producing high-value specialty chemicals, flavors, and fragrances.
• Agrochemical Development: Used in the research and synthesis of novel pesticides and herbicides with specific stereochemical requirements.
• Academic & Industrial R&D: Serves as a versatile chiral synthon in methodological development and complex molecule synthesis.

Basic Information

Item	Details
Product Name	n-(1-Phenylethyl)-1,4-Dioxaspiro[4.5]Decan-8-Amine
CAS No.	937796-19-5
Molecular Formula	C18H27NO2
Molecular Weight	289.42 g/mol
Synonyms	8-[(1R)-1-Phenylethyl]amino-1,4-dioxaspiro[4.5]decane; (R)-N-(1-Phenylethyl)-1,4-dioxaspiro[4.5]decan-8-amine; 1,4-Dioxaspiro[4.5]decan-8-amine, N-(1-phenylethyl)-; 8-[(1S)-1-Phenylethyl]amino-1,4-dioxaspiro[4.5]decane; (S)-N-(1-Phenylethyl)-1,4-dioxaspiro[4.5]decan-8-amine; 1,4-Dioxaspiro[4.5]decan-8-amine, N-(α-methylbenzyl)-; N-(α-Methylbenzyl)-1,4-dioxaspiro[4.5]decan-8-amine
EINECS	Contact for details

Quality Control

Our n-(1-Phenylethyl)-1,4-Dioxaspiro[4.5]Decan-8-Amine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure compliance with exacting research and development standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided to guarantee reproducible performance in your synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee (Specific enantiomer available upon request)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.