Description

6,8-Dichloro-3-(4-Nitrophenyl)-2-Thioxo-2,3-Dihydro-4(1H)-Quinazolinone is a high-value, multi-functional heterocyclic compound that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique quinazolinone core, functionalized with chloro, nitro, and thioxo groups, makes it an indispensable building block for the development of novel bioactive molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating new drug candidates and active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates, particularly those targeting enzymes and receptors where the quinazolinone scaffold is pharmacologically active.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study biological pathways and protein functions in academic and industrial research settings.
• Material Science Research: Investigated as a potential monomer or additive for creating specialized polymers with unique electronic or thermal properties.
• Dye and Pigment Intermediate: Utilized in the synthesis of complex heterocyclic dyes and organic pigments due to its nitro and conjugated system.

Basic Information

Product Name	6,8-Dichloro-3-(4-Nitrophenyl)-2-Thioxo-2,3-Dihydro-4(1H)-Quinazolinone
CAS No.	937601-65-5
Molecular Formula	C14H7Cl2N3O3S
Molecular Weight	368.19 g/mol
Synonyms	6,8-Dichloro-3-(4-nitrophenyl)-2-thioxo-1,2,3,4-tetrahydro-4-quinazolinone; 4(1H)-Quinazolinone, 6,8-dichloro-3-(4-nitrophenyl)-2-thioxo-2,3-dihydro-; 6,8-Dichloro-3-(p-nitrophenyl)-2-thioxo-2,3-dihydro-4(1H)-quinazolinone; 3-(4-Nitrophenyl)-6,8-dichloro-2-thioxo-1,2,3,4-tetrahydroquinazolin-4-one; 6,8-Dichloro-3-(4-nitrophenyl)-2-mercapto-4(3H)-quinazolinone
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Quality Control

Our 6,8-Dichloro-3-(4-Nitrophenyl)-2-Thioxo-2,3-Dihydro-4(1H)-Quinazolinone is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.