Description

1-(6-Iodo-3,4-Dihydroquinolin-1(2H)-Yl)Ethanone is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated quinoline structure. This compound is critical for research and development in medicinal chemistry, serving as a key building block for synthesizing novel drug candidates. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex molecules for drug discovery programs, particularly in oncology and CNS research.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions and other advanced organic transformations to introduce the iodinated quinoline moiety.
• Academic & Institutional Research: Serves as a reference standard and starting material in university and government laboratory research projects.
• Development of Kinase Inhibitors: Potential use in the development of targeted therapies, as the quinoline core is common in many kinase inhibitor scaffolds.

Basic Information

Product Name	1-(6-Iodo-3,4-Dihydroquinolin-1(2H)-Yl)Ethanone
CAS No.	937594-21-3
Molecular Formula	C11H12INO
Molecular Weight	301.13 g/mol
Synonyms	1-(6-Iodo-1,2,3,4-tetrahydroquinolin-1-yl)ethanone; 1-Acetyl-6-iodo-1,2,3,4-tetrahydroquinoline; 6-Iodo-1-acetyl-1,2,3,4-tetrahydroquinoline; Ethanone, 1-(6-iodo-3,4-dihydro-2H-quinolin-1-yl)-; 1-(6-Iodo-3,4-dihydro-2H-quinolin-1-yl)ethanone; 6-Iodo-1-acetyl-1,2,3,4-tetrahydroquinoline; 937594-21-3
EINECS	Contact for details

Quality Control

Our 1-(6-Iodo-3,4-Dihydroquinolin-1(2H)-Yl)Ethanone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.