Description

tert-Butyl 4-Chloro-2-Methoxyphenylcarbamate is a high-purity chemical intermediate of significant importance in advanced organic synthesis. This compound serves as a crucial building block for the development of complex molecules, offering a protected amine functionality that is essential for multi-step synthetic routes. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the production of active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a protected aniline derivative.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where its structural motif is incorporated into bioactive molecules.
• Organic Chemistry Research: Serves as a versatile building block in academic and industrial R&D for constructing complex heterocycles and other advanced organic structures.
• Peptide Mimetics & Drug Discovery: Employed in medicinal chemistry programs to create peptide analogs and small-molecule libraries for biological screening.
• Material Science Precursor: Can be utilized in the synthesis of specialty polymers and functional materials that require specific aromatic amine components.

Basic Information

Product Name	tert-Butyl 4-Chloro-2-Methoxyphenylcarbamate
CAS No.	937072-51-0
Molecular Formula	C12H16ClNO3
Molecular Weight	257.71 g/mol
Synonyms	4-Chloro-2-methoxy-N-(tert-butoxycarbonyl)aniline; 1-(tert-Butoxycarbonylamino)-4-chloro-2-methoxybenzene; tert-Butyl (4-chloro-2-methoxyphenyl)carbamate; BOC-4-Chloro-2-methoxyaniline; N-Boc-4-chloro-2-methoxyaniline; N-(tert-Butoxycarbonyl)-4-chloro-2-methoxyaniline; 4-Chloro-2-methoxybenzenamine N-BOC derivative
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Chloro-2-Methoxyphenylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent quality suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.