Description

7-Chloroquinoline-4-Boronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. This compound matters for its crucial role in facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers developing advanced intermediates for active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting quinoline-based therapeutics.
• Agrochemical Synthesis: Used to create advanced intermediates for crop protection agents and pesticides.
• Material Science Research: Employed in the development of organic electronic materials, ligands for catalysts, and metal-organic frameworks (MOFs).
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic acid partner for forming carbon-carbon bonds with aryl/heteroaryl halides.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses producing bespoke organic compounds for clients.

Basic Information

Product Name	7-Chloroquinoline-4-Boronic Acid
CAS No.	936940-92-0
Molecular Formula	C9H7BClNO2
Molecular Weight	207.42 g/mol
Synonyms	(7-Chloro-4-quinolinyl)boronic acid; 7-Chloro-4-quinolineboronic acid; 4-Borono-7-chloroquinoline; 7-Chloroquinolin-4-ylboronic acid; B-(7-Chloro-4-quinolyl)boronic acid; 936940-92-0; 7-Chloro-4-quinolylboronic acid
EINECS	Contact for details

Quality Control

Our 7-Chloroquinoline-4-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This material is light-sensitive and easily oxidized; prolonged exposure to air, light, or moisture should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.