Description

1-(4-Methyl-5,6,7,8-tetrahydroquinazolin-2-yl)methanamine (Saltdata: 2HCl 1.79H2O) is a high-purity, functionalized tetrahydroquinazoline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile, nitrogen-rich heterocyclic scaffold essential for constructing complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, including the development of new active pharmaceutical ingredients (APIs) and crop protection agents. The product is supplied with CAS No. 936940-73-7.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Agrochemical Development: Serves as a building block for creating new pesticides and herbicides with enhanced efficacy.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis or metal complexation.
• Academic & Institutional R&D: A valuable reagent for fundamental research in heterocyclic and synthetic organic chemistry.

Basic Information

Item	Details
Product Name	1-(4-Methyl-5,6,7,8-tetrahydroquinazolin-2-yl)methanamine (2HCl 1.79H2O)
CAS No.	936940-73-7
Molecular Formula	C₁₁H₁₈Cl₂N₃O₁.₇₉
Molecular Weight	Approx. 312.10 g/mol (as hydrochloride hydrate)
Synonyms	2-(Aminomethyl)-4-methyl-5,6,7,8-tetrahydroquinazoline dihydrochloride hydrate; 1-(4-Methyl-5,6,7,8-tetrahydro-2-quinazolinyl)methanamine hydrochloride hydrate; 4-Methyl-2-(aminomethyl)-5,6,7,8-tetrahydroquinazoline dihydrochloride; Tetrahydroquinazoline-2-methanamine derivative; (4-Methyl-5,6,7,8-tetrahydroquinazolin-2-yl)methanamine HCl salt; Research Code 936940-73-7; 2-(Aminomethyl)-4-methyl-5,6,7,8-tetrahydroquinazoline 2HCl
EINECS	Contact for details

Quality Control

Our 1-(4-Methyl-5,6,7,8-tetrahydroquinazolin-2-yl)methanamine dihydrochloride hydrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for water content, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	8.0 - 10.5 %
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.