Description

1-Oxa-6-Azaspiro[3.3]Heptane-6-Carboxylic Acid, 3,3-Dimethyl-, 1,1-Dimethylethyl Ester is a high-value, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting the central nervous system. It is primarily utilized by pharmaceutical R&D teams, agrochemical innovators, and specialty chemical manufacturers seeking to incorporate its constrained, three-dimensional structure into new molecular entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in neuroscience and psychiatric disorder research.
• Medicinal Chemistry Scaffold: Used to introduce a rigid, spirocyclic motif into lead compounds to improve potency, selectivity, and metabolic stability.
• Agrochemical Research: Serves as a precursor in the development of new crop protection agents with unique modes of action.
• Ligand Synthesis: Employed in the creation of specialized ligands for catalysis and chemical biology applications.
• Academic & Industrial R&D: A valuable reagent for exploring new chemical space and structure-activity relationships (SAR) in various discovery programs.

Basic Information

Product Name	1-Oxa-6-Azaspiro[3.3]Heptane-6-Carboxylic Acid, 3,3-Dimethyl-, 1,1-Dimethylethyl Ester
CAS No.	936850-12-3
Molecular Formula	C12H21NO3
Molecular Weight	227.30 g/mol
Synonyms	tert-Butyl 3,3-dimethyl-1-oxa-6-azaspiro[3.3]heptane-6-carboxylate; 6-(tert-Butoxycarbonyl)-3,3-dimethyl-1-oxa-6-azaspiro[3.3]heptane; 3,3-Dimethyl-1-oxa-6-azaspiro[3.3]heptane-6-carboxylic acid tert-butyl ester; 1-Oxa-6-azaspiro[3.3]heptane-6-carboxylic acid, 3,3-dimethyl-, 1,1-dimethylethyl ester; Boc-Protected 3,3-Dimethyl-1-oxa-6-azaspiro[3.3]heptane; Spirocyclic Boc-Amine Ester
EINECS	Contact for details

Quality Control

Our production of 1-Oxa-6-Azaspiro[3.3]Heptane-6-Carboxylic Acid, 3,3-Dimethyl-, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support development projects with custom synthesis and analytical method development to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to maximize shelf-life stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.