Description

(4-Chloro-3-Hydroxyphenyl)Acetonitrile is a versatile aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a phenolic hydroxyl and a chloro substituent, makes it a critical intermediate for constructing complex pharmacophores and functional materials. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a precursor for active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those with substituted phenol or benzofuran cores.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators.
• Liquid Crystal & OLED Materials: Used in the research and production of advanced electronic display materials and organic light-emitting diodes.
• Polymer Chemistry: Monomer or modifier for creating specialty polymers with specific thermal or chemical resistance properties.
• Dye & Pigment Manufacturing: Intermediate in the synthesis of complex organic dyes and high-performance pigments.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Heck) for creating biaryl structures.
• Chemical Research: Versatile starting material for academic and industrial research in medicinal chemistry and material science.

Basic Information

Product Name	(4-Chloro-3-Hydroxyphenyl)Acetonitrile
CAS No.	936727-34-3
Molecular Formula	C8H6ClNO
Molecular Weight	167.59 g/mol
Synonyms	2-(4-Chloro-3-hydroxyphenyl)acetonitrile; 4-Chloro-3-hydroxybenzeneacetonitrile; (4-Chloro-3-hydroxybenzyl) cyanide; 3-Hydroxy-4-chlorophenylacetonitrile; 2-(4-Chloro-3-hydroxyphenyl)ethanenitrile; 4-Chloro-3-hydroxy-α-tolunitrile; 4-Chloro-3-hydroxybenzyl cyanide
EINECS	Contact for details

Quality Control

Our (4-Chloro-3-Hydroxyphenyl)Acetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of our global B2B clients. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to ensure full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, the container should be amber-colored or stored in a light-proof secondary packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.