Description

(R)-2-(Pyrrolidin-2-Yl)Acetonitrile is a high-value chiral intermediate featuring a nitrile group attached to a pyrrolidine scaffold. This compound is critical for the synthesis of complex, biologically active molecules, enabling precise stereochemical control in pharmaceutical development. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where specific stereochemistry is required for efficacy.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals and complex organic compounds for research and industrial applications.
• Academic and R&D: A valuable reagent for medicinal chemistry research, process chemistry development, and exploring new synthetic methodologies.

Basic Information

Product Name	(R)-2-(Pyrrolidin-2-Yl)Acetonitrile
CAS No.	936630-70-5
Molecular Formula	C6H10N2
Molecular Weight	110.16 g/mol
Synonyms	(R)-2-(2-Pyrrolidinyl)acetonitrile; (R)-2-(Pyrrolidin-2-yl)ethanenitrile; (2R)-2-(Cyanomethyl)pyrrolidine; (R)-2-Cyanomethylpyrrolidine; (R)-Pyrrolidine-2-acetonitrile; (R)-α-(Cyanomethyl)pyrrolidine; (R)-2-Pyrrolidineacetonitrile
EINECS	Contact for details

Quality Control

Our (R)-2-(Pyrrolidin-2-Yl)Acetonitrile is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged operations to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.