Description

4-Chloro-5,8-Difluoro-Quinoline-3-Carbonitrile is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters because its unique halogenated quinoline core serves as a critical precursor for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. Pharmaceutical and agrochemical R&D teams need it to synthesize complex molecules targeting specific biological pathways, leveraging its reactive sites for further functionalization.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides with enhanced efficacy.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology Probes: Utilized in the design of fluorescent tags and molecular probes for diagnostic applications.
• Complex Ligand Synthesis: Acts as a scaffold for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Academic & Industrial R&D: Fundamental reagent for methodological studies in organic chemistry and process development.

Basic Information

Product Name	4-Chloro-5,8-Difluoro-Quinoline-3-Carbonitrile
CAS No.	936497-95-9
Molecular Formula	C10H3ClF2N2
Molecular Weight	224.59 g/mol
Synonyms	4-Chloro-5,8-difluoroquinoline-3-carbonitrile; 5,8-Difluoro-4-chloroquinoline-3-carbonitrile; 3-Cyano-4-chloro-5,8-difluoroquinoline; Quinoline-3-carbonitrile, 4-chloro-5,8-difluoro-; 936497-95-9; 4-Chloro-5,8-difluoro-3-quinolinecarbonitrile
EINECS	Contact for details

Quality Control

Our 4-Chloro-5,8-Difluoro-Quinoline-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.