Description

6-Bromo-4-Chloro-7-Fluoro-Quinoline-3-Carbonitrile is a high-purity, multi-halogenated quinoline derivative serving as a critical advanced pharmaceutical intermediate. Its value lies in its complex molecular scaffold, which is engineered for the synthesis of novel, potent active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, particularly those developing targeted small-molecule therapies and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of kinase inhibitors and other targeted cancer therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel fungicides and herbicides with specific modes of action.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Material Science: Potential precursor for the development of specialty chemicals and functional materials with unique electronic properties.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	6-Bromo-4-Chloro-7-Fluoro-Quinoline-3-Carbonitrile
CAS No.	936497-84-6
Molecular Formula	C10H3BrClFN2
Molecular Weight	285.50 g/mol
Synonyms	6-Bromo-4-chloro-7-fluoroquinoline-3-carbonitrile; 4-Chloro-6-bromo-7-fluoroquinoline-3-carbonitrile; 7-Fluoro-6-bromo-4-chloroquinoline-3-carbonitrile; Quinoline-3-carbonitrile, 6-bromo-4-chloro-7-fluoro-; 936497-84-6; BCFQ-3-CN
EINECS	Contact for details

Quality Control

Our 6-Bromo-4-Chloro-7-Fluoro-Quinoline-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production can align with cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.