Description

5-Bromo-4-Chloro-8-Methyl-Quinoline-3-Carbonitrile is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its complex, halogenated quinoline structure, which serves as a versatile scaffold for constructing sophisticated molecules with targeted biological or material properties. This compound is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzymes or receptors where the quinoline core is pharmacologically active.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its halogenated structure for bioactivity.
• Material Science Building Block: Serves as a monomer or precursor for creating organic electronic materials, such as OLEDs or conductive polymers, due to its electron-deficient quinoline system.
• Ligand Synthesis: Utilized in the preparation of complex ligands for catalysis, where the nitrogen atoms can coordinate to various metals.
• Fluorescent Probe Development: Acts as a core structure for synthesizing dyes and fluorescent markers used in biochemical assays and imaging.
• Academic & Contract Research: Employed in universities and CROs for methodological studies and the exploration of new chemical reactions involving halogenated heterocycles.

Basic Information

Product Name	5-Bromo-4-Chloro-8-Methyl-Quinoline-3-Carbonitrile
CAS No.	936497-83-5
Molecular Formula	C12H6BrClN2
Molecular Weight	293.55 g/mol
Synonyms	5-Bromo-4-chloro-8-methylquinoline-3-carbonitrile; 3-Cyano-5-bromo-4-chloro-8-methylquinoline; 8-Methyl-5-bromo-4-chloroquinoline-3-carbonitrile; Quinoline-3-carbonitrile, 5-bromo-4-chloro-8-methyl-; 936497-83-5
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Chloro-8-Methyl-Quinoline-3-Carbonitrile is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.