Description

8-Bromo-4-Chloro-Quinoline-3-Carbonitrile is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries to construct novel quinoline-based compounds with targeted biological or functional properties.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates with quinoline scaffolds targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of functionalized quinoline derivatives.
• Material Science: Serves as a building block for creating organic electronic materials, ligands for metal-organic frameworks (MOFs), and specialty dyes or pigments.
• Chemical Biology & Probe Development: Employed in the design and synthesis of molecular probes and inhibitors for studying biological pathways and enzyme functions.
• Academic & Contract Research: A valuable reagent for methodology development and exploratory synthesis in university and CRO laboratory settings.

Basic Information

Product Name	8-Bromo-4-Chloro-Quinoline-3-Carbonitrile
CAS No.	936497-82-4
Molecular Formula	C10H4BrClN2
Molecular Weight	267.51 g/mol
Synonyms	8-Bromo-4-chloroquinoline-3-carbonitrile; 3-Cyano-8-bromo-4-chloroquinoline; 4-Chloro-8-bromoquinoline-3-carbonitrile; Quinoline-3-carbonitrile, 8-bromo-4-chloro-; 936497-82-4; 8-Bromo-4-chloro-3-cyanoquinoline
EINECS	Contact for details

Quality Control

Our 8-Bromo-4-Chloro-Quinoline-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.