Description

4-Bromo-3-Methyl-8-(Trifluoromethyl)Quinoline is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which combines bromine and trifluoromethyl substituents to enable precise chemical modifications and modulate electronic properties. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Serves as a core structure for developing new herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science: Used in the development of organic semiconductors, light-emitting diodes (OLEDs), and other advanced electronic materials due to its electron-deficient quinoline core.
• Chemical Biology: Employed as a molecular probe or tag in bioconjugation and proteomics research to study biological interactions.
• Catalyst Ligand Synthesis: Acts as a starting material for creating sophisticated nitrogen-containing ligands used in transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specialized fluorinated and halogenated intermediates.

Basic Information

Product Name	4-Bromo-3-Methyl-8-(Trifluoromethyl)Quinoline
CAS No.	936352-89-5
Molecular Formula	C11H6BrF3N
Molecular Weight	289.07 g/mol
Synonyms	8-(Trifluoromethyl)-4-bromo-3-methylquinoline; 4-Bromo-3-methyl-8-(trifluoromethyl)quinoline; 3-Methyl-4-bromo-8-trifluoromethylquinoline; Quinoline, 4-bromo-3-methyl-8-(trifluoromethyl)-; 936352-89-5; 4-Bromo-3-methyl-8-trifluoromethylquinoline
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Methyl-8-(Trifluoromethyl)Quinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.