Description

(4-Ethynylphenyl)Methanamine Hydrochloride CAS NO 935528-07-7 is a high-purity organic building block featuring both an amine and an ethynyl functional group. This compound is critical for advanced organic synthesis, particularly in the development of complex molecular architectures. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for applications such as drug discovery and polymer synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for targeted therapies.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its reactive ethynyl group for structural diversification.
• Material Science: Acts as a monomer or cross-linking agent in the production of specialty polymers and advanced functional materials.
• Chemical Synthesis: Employed in Sonogashira coupling and other palladium-catalyzed reactions to create conjugated systems and complex organic molecules.
• Bioconjugation: Utilized for labeling biomolecules (e.g., proteins, peptides) due to the reactivity of the alkyne group in click chemistry reactions.
• Ligand Synthesis: A precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	(4-Ethynylphenyl)Methanamine Hydrochloride
CAS No.	935528-07-7
Molecular Formula	C9H10ClN
Molecular Weight	167.63 g/mol
Synonyms	1-(4-Ethynylphenyl)methanamine hydrochloride; 4-(Aminomethyl)phenylacetylene hydrochloride; (4-Ethynylbenzyl)amine hydrochloride; p-Ethynylbenzylamine hydrochloride; 4-Ethynylbenzenemethanamine hydrochloride; 4-(Aminomethyl)phenylacetylene HCl; 4-Ethynylbenzylamine HCl; Benzenemethanamine, 4-ethynyl-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our (4-Ethynylphenyl)Methanamine Hydrochloride is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support development under cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.