Description

Methanesulfonic Acid, 1,1,1-Trifluoro-, [2,2'-Binaphthalen]-6-Yl Ester is a specialized fluorinated sulfonate ester building block of significant interest in advanced organic synthesis. Its value lies in its unique molecular architecture, combining a trifluoromethanesulfonate (triflate) leaving group with a bulky, chiral binaphthyl scaffold, making it a critical reagent for constructing complex, stereodefined molecules. This high-purity intermediate is primarily needed by research and development laboratories in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block or activating agent in the synthesis of complex drug candidates, particularly for introducing stereocenters or creating novel molecular architectures.
• Agrochemical Research: Used in the development of new pesticides and herbicides where the binaphthyl moiety can impart specific biological activity and environmental stability.
• Catalyst Ligand Synthesis: Acts as a precursor for synthesizing sophisticated chiral ligands used in asymmetric catalysis, such as for hydrogenation or cross-coupling reactions.
• Advanced Material Science: Employed in the creation of specialty polymers, liquid crystals, or organic electronic materials that require rigid, chiral components.
• Organic Methodology Development: Utilized by academic and industrial research groups to develop new synthetic transformations leveraging the reactivity of the triflate group.

Basic Information

Product Name	Methanesulfonic Acid, 1,1,1-Trifluoro-, [2,2'-Binaphthalen]-6-Yl Ester
CAS No.	935472-81-4
Molecular Formula	C21H13F3O3S
Molecular Weight	402.39 g/mol
Synonyms	(R)- or (S)-6-Binaphthyl Triflate; 1,1,1-Trifluoro-6-(1,1'-binaphthalen-2-yl) methanesulfonate; [1,1'-Binaphthalene]-6-yl trifluoromethanesulfonate; 6-Binaphthyl Triflate Ester; 6-(2-Naphthyl)naphthalen-2-yl trifluoromethanesulfonate; Trifluoromethanesulfonic Acid [1,1'-Binaphthalen]-6-yl Ester; (6-Binaphthyl) Triflate
EINECS	Contact for details

Quality Control

Our Methanesulfonic Acid, 1,1,1-Trifluoro-, [2,1'-Binaphthalen]-6-Yl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for research and process development. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and chiral analysis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Chiral Purity (HPLC)	≥ 99.0% ee (for enantiomerically pure grade)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.