Description

3-(Hydroxymethyl)Azetidin-3-Ol Hydrochloride is a high-purity, functionalized azetidine building block essential for modern pharmaceutical and agrochemical research. This compound matters as a versatile chiral scaffold for constructing complex molecules, enabling the development of novel active ingredients with enhanced efficacy. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and crop protection industries for applications in drug discovery and advanced material synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of β-lactam antibiotics, protease inhibitors, and other bioactive molecules.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators that require specific stereochemistry.
• Chemical Biology Probes: Serves as a core structure for designing enzyme inhibitors and molecular probes to study biological pathways.
• Material Science: Potential monomer or cross-linking agent for creating specialized polymers with unique thermal or mechanical properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring a defined stereogenic center within a strained ring system.

Basic Information

Product Name	3-(Hydroxymethyl)Azetidin-3-Ol Hydrochloride
CAS No.	934665-98-2
Molecular Formula	C4H9NO2 • HCl
Molecular Weight	139.58 g/mol (Free base: 103.12 g/mol)
Synonyms	3-(Hydroxymethyl)-3-hydroxyazetidine hydrochloride; 3-Hydroxy-3-(hydroxymethyl)azetidine hydrochloride; Azetidin-3-ol, 3-(hydroxymethyl)-, hydrochloride; 3-Azetidinol, 3-(hydroxymethyl)-, hydrochloride; 3-Hydroxyazetidine-3-methanol hydrochloride; (3-Hydroxyazetidin-3-yl)methanol hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 3-(Hydroxymethyl)Azetidin-3-Ol Hydrochloride is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.