Description

1-Oxa-5-Azaspiro[2.3]Hexane-5-Carboxylic Acid Phenylmethyl Ester is a high-value, spirocyclic heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique structural framework, which is pivotal in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require complex heterocyclic cores.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of novel polymers and functional organic materials with specific electronic or structural properties.
• Chemical Biology Probes: Utilized as a building block for synthesizing molecular probes to study biological pathways and enzyme functions.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new chemical spaces in both academic and corporate research laboratories.

Basic Information

Product Name	1-Oxa-5-Azaspiro[2.3]Hexane-5-Carboxylic Acid Phenylmethyl Ester
CAS No.	934664-22-9
Molecular Formula	C12H13NO3
Molecular Weight	219.24 g/mol
Synonyms	Benzyl 1-oxa-5-azaspiro[2.3]hexane-5-carboxylate; 5-(Benzyloxycarbonyl)-1-oxa-5-azaspiro[2.3]hexane; 1-Oxa-5-azaspiro[2.3]hexane-5-carboxylic acid benzyl ester; Spiro[oxirane-2,1'-azetidine]-1'-carboxylic acid phenylmethyl ester; Cbz-Protected 1-Oxa-5-azaspiro[2.3]hexane; 934664-22-9; Benzyl 5-azaspiro[2.3]hexane-5-carboxylate 1-oxide (alternative representation)
EINECS	Contact for details

Quality Control

Our 1-Oxa-5-Azaspiro[2.3]Hexane-5-Carboxylic Acid Phenylmethyl Ester is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee batch-to-batch consistency and support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.