Description

2-Bromo-1-Ethoxy-4-Trifluoromethyl-Benzene is a high-purity, multi-functional halogenated aromatic building block. This compound is valued for its unique trifluoromethyl and bromo-ethoxy substitution pattern, which imparts significant electronic and steric properties for advanced synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical sectors. The molecule serves as a critical intermediate for constructing complex active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting CNS disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, leveraging the trifluoromethyl group for enhanced bioavailability and stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent for advanced polymers and liquid crystals with specific optical or electronic properties.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Organic Synthesis Reagent: Employed in academic and industrial research for constructing complex aromatic and heteroaromatic systems.
• Fluorine Chemistry Research: A valuable compound for studying the influence of the trifluoromethyl group on reaction kinetics and molecular interactions.

Basic Information

Product Name	2-Bromo-1-Ethoxy-4-Trifluoromethyl-Benzene
CAS No.	934495-35-9
Molecular Formula	C9H8BrF3O
Molecular Weight	269.06 g/mol
Synonyms	1-Bromo-2-ethoxy-4-(trifluoromethyl)benzene; 2-Bromo-1-ethoxy-4-(trifluoromethyl)benzene; 2-Bromo-α,α,α-trifluoro-p-ethoxy toluene; 4-Trifluoromethyl-2-bromo-1-ethoxybenzene; 2-Bromo-4-(trifluoromethyl)phenetole; 1-Ethoxy-2-bromo-4-trifluoromethylbenzene; Benzene, 2-bromo-1-ethoxy-4-(trifluoromethyl)-; p-Ethoxy-o-bromobenzotrifluoride
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-Ethoxy-4-Trifluoromethyl-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.