Description

6-Bromo-1-[(1S)-1-[[[(1,1-Dimethylethyl)dimethylsilyl]oxy]methyl]-2-methylpropyl]-7-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid ethyl ester is a sophisticated, high-purity synthetic intermediate characterized by its complex, multi-functional molecular architecture. This compound is of critical importance in advanced pharmaceutical research and development, particularly in the synthesis of novel fluoroquinolone-based antibacterial agents. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for constructing complex molecular scaffolds.

Application

• Key Intermediate in Fluoroquinolone Antibiotic Synthesis: Serves as a crucial building block for the development of next-generation antibacterial drugs.
• Pharmaceutical Research & Development (R&D): Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry & Scale-Up: Employed in the development and optimization of commercial-scale synthetic routes for active pharmaceutical ingredients (APIs).
• Custom Synthesis & Contract Manufacturing: A vital component for CDMOs (Contract Development and Manufacturing Organizations) offering specialized synthesis services.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and advanced organic synthesis methodologies.

Basic Information

Product Name	6-Bromo-1-[(1S)-1-[[[(1,1-Dimethylethyl)dimethylsilyl]oxy]methyl]-2-methylpropyl]-7-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid ethyl ester
CAS No.	934161-52-1
Molecular Formula	C24H32BrFNO4Si
Molecular Weight	540.51 g/mol
Synonyms	Ethyl 6-bromo-1-[(1S)-1-[[(tert-butyldimethylsilyl)oxy]methyl]-2-methylpropyl]-7-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate; 6-Bromo-7-fluoro-1-[(1S)-1-[[(tert-butyldimethylsilyl)oxy]methyl]-2-methylpropyl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid ethyl ester; TBDMS-protected fluoroquinolone intermediate; (S)-TBDMS-O-desmethyl moxifloxacin intermediate derivative; Advanced fluoroquinolone synthon; 934161-52-1
EINECS	Contact for details

Quality Control

This high-value intermediate is produced under strict quality control protocols to ensure batch-to-batch consistency and purity suitable for pharmaceutical applications. Our quality system employs advanced analytical techniques including HPLC, GC, NMR, and MS for comprehensive characterization. A detailed Certificate of Analysis (COA) is provided with each batch, documenting identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be stored away from light. Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Store separately from strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Single Maximum Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.