Description

8-Fluoro-4(1H)-Quinolinone is a fluorinated heterocyclic compound that serves as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in its role as a versatile building block for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This high-purity intermediate is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Material Science Precursor: Serves as a starting material for creating advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Synthesis Scaffold: Employed in academic and industrial R&D for constructing complex quinoline-based libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Fluorine Chemistry Studies: Acts as a model compound for investigating the effects of fluorine substitution on the physicochemical properties of heterocyclic systems.

Basic Information

Product Name	8-Fluoro-4(1H)-Quinolinone
CAS No.	934000-16-5
Molecular Formula	C9H6FNO
Molecular Weight	163.15 g/mol
Synonyms	8-Fluoro-4-hydroxyquinoline; 8-Fluoro-4-quinolone; 8-Fluoro-1H-quinolin-4-one; 4(1H)-Quinolinone, 8-fluoro-; 8-Fluoro-4-quinolinol; 8-Fluoro-4(1H)-quinolone; 8-Fluoro-4-hydroxy-1H-quinoline
EINECS	Contact for details

Quality Control

Our 8-Fluoro-4(1H)-Quinolinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.