Description

Quinoline, 2-[(4R)-4,5-Dihydro-4-(Phenylmethyl)-2-Oxazolyl]- is a high-purity, chiral oxazoline-substituted quinoline derivative, serving as a sophisticated building block in advanced organic synthesis. Its core value lies in its role as a key chiral ligand precursor or intermediate for the development of asymmetric catalysts used in pharmaceutical and fine chemical manufacturing. This compound is essential for research and production teams in the pharmaceutical, agrochemical, and specialty chemical industries who require enantiomerically pure intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of active pharmaceutical ingredients (APIs) requiring high enantiomeric purity.
• Asymmetric Catalyst Ligand Synthesis: Serves as a precursor for novel oxazoline-based ligands used in transition metal catalysis for enantioselective reactions.
• Agrochemical Research: Used in the development of new, more effective chiral pesticides and herbicides.
• Material Science: Potential monomer or additive for creating advanced polymers with specific optical or electronic properties.
• Academic & Industrial R&D: A valuable tool for chemists exploring new methodologies in asymmetric synthesis and organometallic chemistry.

Basic Information

Product Name	Quinoline, 2-[(4R)-4,5-Dihydro-4-(Phenylmethyl)-2-Oxazolyl]-
CAS No.	933992-48-4
Molecular Formula	C19H18N2O
Molecular Weight	290.36 g/mol
Synonyms	(R)-2-(4-Benzyl-4,5-dihydrooxazol-2-yl)quinoline; (4R)-4-Benzyl-2-(quinolin-2-yl)-4,5-dihydro-1,3-oxazole; 2-[(4R)-4-Benzyl-4,5-dihydro-1,3-oxazol-2-yl]quinoline; (R)-4-Benzyl-2-(2-quinolyl)-2-oxazoline; Quinoline, 2-(4,5-dihydro-4-(phenylmethyl)-2-oxazolyl)-, (4R)-; (R)-4-Benzyl-2-(quinolin-2-yl)-4,5-dihydrooxazole; (R)-2-(Quinolin-2-yl)-4-benzyl-4,5-dihydrooxazole
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure high chemical and enantiomeric purity. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.