Description

(5,6,7,8-Tetrahydro-[1,8]Naphthyridin-3-Yl)-Methylamine is a high-purity, advanced pharmaceutical intermediate belonging to the naphthyridine class of heterocyclic compounds. This specialized chemical is critical for research and development in medicinal chemistry, serving as a key building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of complex drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of new molecules.
• API Development: Serves as a building block in the development and scale-up of new Active Pharmaceutical Ingredients (APIs) for clinical trials and commercial production.
• Chemical Biology Probes: Employed in the design and synthesis of chemical probes to study biological pathways and identify new drug targets.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Academic Research: Used in university and institutional laboratories for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	(5,6,7,8-Tetrahydro-[1,8]Naphthyridin-3-Yl)-Methylamine
CAS No.	933695-41-1
Molecular Formula	C10H15N3
Molecular Weight	177.25 g/mol
Synonyms	3-(Aminomethyl)-5,6,7,8-tetrahydro-1,8-naphthyridine; 5,6,7,8-Tetrahydro-1,8-naphthyridin-3-ylmethanamine; (5,6,7,8-Tetrahydro[1,8]naphthyridin-3-yl)methanamine; 3-(Aminomethyl)-5,6,7,8-tetrahydro[1,8]naphthyridine; Tetrahydro-naphthyridinyl-methylamine; CAS 933695-41-1
EINECS	Contact for details

Quality Control

Our (5,6,7,8-Tetrahydro-[1,8]Naphthyridin-3-Yl)-Methylamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.