Description

2-Bromo-1H-Imidazole-4-Carbaldehyde is a versatile and highly functionalized heterocyclic building block, essential for advanced organic synthesis. Its core value lies in the strategic positioning of both a bromine atom and an aldehyde group on the imidazole scaffold, enabling a wide range of coupling and condensation reactions. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in medicinal chemistry programs targeting novel therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule drugs.
• Agrochemical Synthesis: Used in the development of novel fungicides, herbicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized N-heterocyclic carbene (NHC) ligands and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and functional polymers.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions.

Basic Information

Product Name	2-Bromo-1H-Imidazole-4-Carbaldehyde
CAS No.	933690-26-7
Molecular Formula	C4H3BrN2O
Molecular Weight	174.98 g/mol
Synonyms	2-Bromo-1H-imidazole-4-carboxaldehyde; 4-Formyl-2-bromoimidazole; 2-Bromoimidazole-4-carbaldehyde; 2-Bromo-4-formylimidazole; 1H-Imidazole-4-carboxaldehyde, 2-bromo-; 933690-26-7; 2-Bromo-1H-imidazole-4-carbaldehyde
EINECS	Contact for details

Quality Control

Our 2-Bromo-1H-Imidazole-4-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.