Description

4-Amino-6-Fluoroquinoline-3-Carboxylic Acid is a high-value, multifunctional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its unique molecular scaffold, which combines a quinoline core with strategically positioned amino, fluoro, and carboxylic acid functional groups, enabling precise molecular modifications. This compound is critically needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly in the development of new quinolone-based drugs and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel fluoroquinolone antibiotics and other bioactive molecules targeting bacterial infections.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and pesticides with enhanced efficacy and selectivity.
• Material Science: Used in the research and development of advanced organic materials, including ligands for catalysis and components for organic electronics.
• Chemical Synthesis: A versatile synthon for constructing complex heterocyclic compounds in academic and industrial research laboratories.
• Bioconjugation & Probe Development: The carboxylic acid group allows for coupling to biomolecules or solid supports, useful in creating diagnostic probes or targeted delivery systems.

Basic Information

Product Name	4-Amino-6-Fluoroquinoline-3-Carboxylic Acid
CAS No.	933688-20-1
Molecular Formula	C10H7FN2O2
Molecular Weight	206.18 g/mol
Synonyms	6-Fluoro-4-aminoquinoline-3-carboxylic acid; 4-Amino-6-fluoro-3-quinolinecarboxylic acid; 3-Quinolinecarboxylic acid, 4-amino-6-fluoro-; 4-Amino-6-fluoroquinoline-3-carboxylate; AFQCA; 933688-20-1 (CAS); 4-Amino-6-fluoro-quinoline-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4-Amino-6-Fluoroquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.