Description

6-Nitro-4-Trifluoromethyl-Benzo[1,3]Dioxol-2-One is a specialized fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of a nitro group and a trifluoromethyl group attached to a benzo[1,3]dioxol-2-one scaffold, enabling precise molecular modifications. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Key pharmaceutical intermediate for the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Advanced agrochemical intermediate in the research and development of new herbicides and insecticides, leveraging the bioactivity of the nitro and trifluoromethyl motifs.
• Versatile fluorinated building block in medicinal chemistry for introducing lipophilicity and metabolic stability into lead compounds.
• Precursor in material science for the synthesis of specialty polymers and functional materials with tailored electronic or surface properties.
• Used in organic synthesis research to study novel cyclization and substitution reactions involving fused dioxolone rings.

Basic Information

Product Name	6-Nitro-4-Trifluoromethyl-Benzo[1,3]Dioxol-2-One
CAS No.	933673-31-5
Molecular Formula	C8H2F3NO5
Molecular Weight	249.10 g/mol
Synonyms	6-Nitro-4-(trifluoromethyl)-2H-1,3-benzodioxol-2-one; 4-(Trifluoromethyl)-6-nitro-1,3-benzodioxol-2-one; 6-Nitro-4-trifluoromethyl-1,3-benzodioxol-2-one; 2H-1,3-Benzodioxol-2-one, 6-nitro-4-(trifluoromethyl)-; Benzo[1,3]dioxol-2-one, 6-nitro-4-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 6-Nitro-4-Trifluoromethyl-Benzo[1,3]Dioxol-2-One is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.