Description

2-Fluoro-5-Iodobenzaldehyde Dimethyl Acetal is a versatile and high-purity fluorinated and iodinated aromatic building block. This compound is critical for advanced organic synthesis, particularly in the construction of complex molecules where precise halogen substitution is required. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications such as cross-coupling reactions and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those requiring halogenated aromatic scaffolds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides where the fluorine and iodine substituents modulate biological activity.
• Material Science Research: Serves as a building block for creating advanced organic materials, including liquid crystals and organic semiconductors.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Stille couplings to form new carbon-carbon bonds.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags for imaging and diagnostic applications due to its halogen handles.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	2-Fluoro-5-Iodobenzaldehyde Dimethyl Acetal
CAS No.	933585-46-7
Molecular Formula	C9H10FIO2
Molecular Weight	296.08 g/mol
Synonyms	1-Fluoro-4-iodo-2-(dimethoxymethyl)benzene; Benzaldehyde, 2-fluoro-5-iodo-, dimethyl acetal; (2-Fluoro-5-iodophenyl)dimethoxymethane; 2-Fluoro-5-iodobenzaldehyde dimethylacetal; Dimethyl (2-fluoro-5-iodobenzylidene) acetal; α,α-Dimethoxy-2-fluoro-5-iodotoluene
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Iodobenzaldehyde Dimethyl Acetal is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee batch-to-batch consistency and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.