Description

4-Bromo-7-Nitroquinoline is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its dual functionalization, featuring both a bromo substituent for cross-coupling reactions and a nitro group amenable to reduction, enabling the rapid construction of complex quinoline-based scaffolds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs), functional materials, and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting infectious diseases, cancer, and central nervous system disorders.
• Agrochemical Research: Used to develop novel quinoline-based fungicides, herbicides, and insecticides with enhanced efficacy.
• Material Science: Serves as a building block for creating organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs).
• Chemical Biology: Employed in the design and synthesis of molecular probes, enzyme inhibitors, and fluorescent tags for biological studies.
• Academic & R&D: A fundamental reagent for methodological development in cross-coupling (e.g., Suzuki, Buchwald-Hartwig) and nitro-group manipulation chemistry.
• Dye & Pigment Industry: Acts as an intermediate for synthesizing specialized quinoline dyes and colorants.

Basic Information

Product Name	4-Bromo-7-Nitroquinoline
CAS No.	933486-43-2
Molecular Formula	C9H5BrN2O2
Molecular Weight	253.05 g/mol
Synonyms	7-Nitro-4-bromoquinoline; 4-Bromo-7-nitro-quinoline; Quinoline, 4-bromo-7-nitro-; 4-Brom-7-nitrochinolin; 4-Bromo-7-nitro-chinolin; 4-Br-7-NO2-Quinoline
EINECS	Contact for details

Quality Control

Our 4-Bromo-7-Nitroquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.