Description

n-Boc-α-(Phenylsulfonyl)Isobutylamine is a high-purity, protected amine building block essential for advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those requiring sulfonamide or protected amine functionalities.
• Peptidomimetic Synthesis: Used in the construction of peptide analogs and mimetics for drug discovery programs targeting various diseases.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, and insecticides with tailored properties.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for asymmetric catalysis and metal-organic frameworks.
• Custom Chemical Synthesis: A versatile reagent for contract research organizations (CROs) and CDMOs producing bespoke compounds for clients.
• Academic Research: Used in university and institutional labs for methodological development and exploring new chemical reactions.

Basic Information

Product Name	n-Boc-α-(Phenylsulfonyl)Isobutylamine
CAS No.	932710-66-2
Molecular Formula	C₁₅H₂₃NO₄S
Molecular Weight	313.41 g/mol
Synonyms	tert-Butyl N-[(2-methyl-1-phenylsulfonylpropan-2-yl)]carbamate; 1-[(tert-Butoxycarbonyl)amino]-2-methyl-2-(phenylsulfonyl)propane; N-Boc-α-(Phenylsulfonyl)isobutylamine; N-(tert-Butoxycarbonyl)-α-(phenylsulfonyl)isobutylamine; 2-Methyl-2-[(phenylsulfonyl)methyl]propyl carbamic acid tert-butyl ester; Boc-ASIB-OH (common abbreviation); (2-Methyl-1-phenylsulfonylpropan-2-yl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our n-Boc-α-(Phenylsulfonyl)Isobutylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with client specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.