Description

4-((4-Bromo-2-Fluorophenyl)Amino)-6-Methoxyquinazolin-7-Ol Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 932016-10-9. This quinazoline derivative is a critical building block in the synthesis of targeted therapeutic agents, offering researchers and manufacturers a reliable and well-characterized starting material. It is primarily utilized by pharmaceutical R&D teams and fine chemical producers engaged in the development of novel kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel kinase inhibitor candidates for oncology and other therapeutic areas.
• Biochemical Research: Used as a reference standard or probe compound in enzymatic assays and structure-activity relationship (SAR) studies.
• API Development: Serves as a crucial synthetic building block during the process development and scale-up of active pharmaceutical ingredients (APIs).
• Academic Research: Employed in university and institutional laboratories for medicinal chemistry projects and drug discovery programs.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and cGMP production.

Basic Information

Product Name	4-((4-Bromo-2-Fluorophenyl)Amino)-6-Methoxyquinazolin-7-Ol Hydrochloride
CAS No.	932016-10-9
Molecular Formula	C15H12BrFN3O2 • HCl
Molecular Weight	416.64 g/mol (Free base: 380.18 g/mol)
Synonyms	4-((4-Bromo-2-fluorophenyl)amino)-6-methoxy-7-quinazolinol hydrochloride; 6-Methoxy-4-[(4-bromo-2-fluorophenyl)amino]-7-quinazolinol hydrochloride; 7-Hydroxy-6-methoxy-N-(4-bromo-2-fluorophenyl)quinazolin-4-amine hydrochloride; 932016-10-9; 4-[(4-Bromo-2-fluorophenyl)amino]-6-methoxyquinazolin-7-ol HCl
EINECS	Contact for details

Quality Control

Our 4-((4-Bromo-2-Fluorophenyl)Amino)-6-Methoxyquinazolin-7-Ol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.