Description

9-Amino-(9-deoxy)epi-dihydroquinine trihydrochloride is a high-purity, advanced pharmaceutical intermediate derived from the cinchona alkaloid scaffold. This compound is valued for its role as a key chiral building block and ligand in asymmetric synthesis and catalysis, enabling the production of enantiomerically pure compounds. It is essential for research and development laboratories, process chemists, and manufacturers in the pharmaceutical and fine chemical industries focused on developing novel therapeutics and high-value specialty chemicals.

Application

• As a chiral ligand or catalyst in asymmetric synthesis reactions, such as asymmetric hydrogenation or alkylation.
• As a key synthetic intermediate in the research and development of novel active pharmaceutical ingredients (APIs).
• In the preparation of chiral phase-transfer catalysts for enantioselective transformations.
• For use in methodological development within academic and industrial organic chemistry research.
• As a reference standard for analytical method development and quality control in pharmaceutical manufacturing.
• In the synthesis of complex natural product analogs and specialty fine chemicals.

Basic Information

Product Name	9-Amino-(9-deoxy)epi-dihydroquinine trihydrochloride
CAS No.	931098-91-8
Molecular Formula	C20H28Cl3N3O
Molecular Weight	432.81 g/mol
Synonyms	(8S,9R)-9-Amino-10,11-dihydro-6'-methoxycinchonan-9-ol trihydrochloride; 9-Amino-9-deoxyepi-dihydroquinine trihydrochloride; 9-ADEDQ trihydrochloride; (9R)-9-Amino-10,11-dihydro-6'-methoxycinchonan-9-ol trihydrochloride; 9-Aminoepi-dihydroquinine trihydrochloride; 9-NH2-epi-dihydroquinine HCl; Epi-9-amino-dihydroquinine trihydrochloride
EINECS	Contact for details

Quality Control

Our 9-Amino-(9-deoxy)epi-dihydroquinine trihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D and fine chemical synthesis. Certificates of Analysis (COA) with detailed batch-specific results are provided.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.