Description

Isosalvianolic Acid B is a bioactive phenolic acid compound derived from the traditional medicinal herb *Salvia miltiorrhiza* (Danshen). This high-purity reference standard is critical for ensuring the quality, safety, and efficacy of herbal extracts and pharmaceutical formulations. It serves as an essential analytical tool for researchers and manufacturers in the pharmaceutical, nutraceutical, and herbal medicine industries, particularly for standardization and bioactivity studies.

Application

• Pharmaceutical Reference Standard: Used for the identification, assay, and quality control of Danshen extracts and related finished products in pharmacopoeial methods.
• Nutraceutical & Dietary Supplement Formulation: Acts as a key marker compound for standardizing herbal supplements to ensure consistent potency and bioactivity.
• Biomedical & Pharmacological Research: Employed in *in vitro* and *in vivo* studies to investigate its antioxidant, cardioprotective, and neuroprotective mechanisms of action.
• Cosmeceutical Development: Incorporated into advanced skincare formulations for its potent antioxidant properties, helping to protect skin from oxidative stress.
• Analytical Method Development: Serves as a primary calibrant for developing and validating HPLC, LC-MS, and other chromatographic methods for phenolic acid analysis.

Basic Information

Product Name	Isosalvianolic Acid B
CAS No.	930573-88-9
Molecular Formula	C36H30O16
Molecular Weight	718.62 g/mol
Synonyms	Isosalvianolic acid B; Salvianolic acid B isomer; Danshensu derivative; Lithospermic acid B isomer; 2-[[(2E)-3-[2-[(1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]carbonyl]-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy]-3-(3,4-dihydroxyphenyl)propanoic acid
EINECS	Contact for details

Quality Control

Our Isosalvianolic Acid B is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, MS, NMR). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or manufacturing standards. Specifications can be tailored to meet the requirements of pharmacopoeial guidelines (e.g., USP, EP) for reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This compound is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.