Description

3-(Fmoc-Amino)Cyclopentanecarboxylic Acid CAS NO 929976-34-1 is a high-purity, protected amino acid derivative essential for advanced peptide synthesis. This compound serves as a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled introduction of cyclopentane-based structures into peptide chains. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, peptidomimetics, and other bioactive molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key Fmoc-protected intermediate for the stepwise construction of complex peptides.
• Peptidomimetic Drug Discovery: Incorporation of the constrained cyclopentane ring to enhance metabolic stability and receptor binding affinity in drug candidates.
• Combinatorial Chemistry Libraries: Used to generate diverse arrays of compounds for high-throughput screening against biological targets.
• Bioconjugation: Serves as a linker or spacer molecule for attaching peptides to other biomolecules, surfaces, or reporter groups.
• Academic & Industrial Research: Fundamental research tool in medicinal chemistry, chemical biology, and structural biology studies.
• Custom Oligopeptide Production: Employed by CROs and CDMOs for the custom synthesis of non-standard peptides for clients.

Basic Information

Product Name	3-(Fmoc-Amino)Cyclopentanecarboxylic Acid
CAS No.	929976-34-1
Molecular Formula	C21H21NO4
Molecular Weight	351.40 g/mol
Synonyms	Fmoc-3-Aminocyclopentanecarboxylic Acid; 3-[(9-Fluorenylmethoxycarbonyl)amino]cyclopentanecarboxylic Acid; 3-(Fmoc-amino)cyclopentane-1-carboxylic acid; 1-Carboxy-3-(Fmoc-amino)cyclopentane; (1R,3S)-rel-3-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]cyclopentanecarboxylic Acid; Fmoc-Acp(3)-OH; Fmoc-3-Acp-OH
EINECS	Contact for details

Quality Control

Our 3-(Fmoc-Amino)Cyclopentanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.