Description

1-Oxaspiro[2.5]Oct-4-Ene-2-Carbonitrile, 2-Methyl- is a high-value, specialized spirocyclic nitrile building block used in advanced organic synthesis. Its unique fused ring structure makes it a critical intermediate for constructing complex molecular architectures in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process development scientists working on novel active ingredients, particularly in the development of new therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel spirocyclic and fused-ring drug candidates, including potential central nervous system (CNS) and anti-infective agents.
• Agrochemical Research: Used in the development of new pesticides and herbicides with novel modes of action, leveraging its complex, three-dimensional scaffold.
• Material Science Chemistry: Serves as a precursor for specialty polymers and advanced organic materials requiring specific steric and electronic properties.
• Asymmetric Synthesis: Acts as a chiral building block or a precursor to chiral auxiliaries and ligands for catalytic processes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Fine Chemical Manufacturing: Employed in custom synthesis and contract manufacturing for producing high-value, low-volume specialty chemicals.

Basic Information

Product Name	1-Oxaspiro[2.5]Oct-4-Ene-2-Carbonitrile, 2-Methyl-
CAS No.	929624-37-3
Molecular Formula	C9H11NO
Molecular Weight	149.19 g/mol
Synonyms	2-Methyl-1-oxaspiro[2.5]oct-4-ene-2-carbonitrile; 2-Methyl-1-oxaspiro[2.5]oct-4-ene-2-carbonitrile; 1-Oxaspiro[2.5]oct-4-ene-2-carbonitrile, 2-methyl-; Spiro[2.5]oct-4-ene-2-carbonitrile, 1-oxa-2-methyl-; 2-Methyl-1-oxa-2-azaspiro[2.5]oct-4-ene-2-carbonitrile (related structural name); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 1-Oxaspiro[2.5]Oct-4-Ene-2-Carbonitrile, 2-Methyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP standards for pharmaceutical applications and can tailor purity grades to meet specific research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.