Description

4-Cyano-4-(Toluene-4-Sulfonyloxymethyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate designed for complex organic synthesis. This compound is critical for research and development in medicinal chemistry, serving as a key building block for novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of complex piperidine-based drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new drug discovery programs.
• Process Chemistry Development: Serves as a key starting material or intermediate in scaling up synthetic routes from laboratory to pilot plant scale.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the production of specialized compounds for clients.
• Protecting Group Chemistry: The tert-butyloxycarbonyl (Boc) and tosyl (Ts) groups are valuable for protecting amines and alcohols during multi-step syntheses.

Basic Information

Product Name	4-Cyano-4-(Toluene-4-Sulfonyloxymethyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	929302-00-1
Molecular Formula	C19H26N2O5S
Molecular Weight	394.49 g/mol
Synonyms	1-Boc-4-cyano-4-[(p-toluenesulfonyloxy)methyl]piperidine; 4-Cyano-4-[(4-methylphenyl)sulfonyloxymethyl]piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-cyano-4-[[(4-methylphenyl)sulfonyl]oxymethyl]piperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-cyano-4-[(p-tolylsulfonyloxy)methyl]piperidine; 4-Cyano-4-(p-toluenesulfonyloxymethyl)-1-N-Boc-piperidine; 929302-00-1; Boc-4-CN-4-CH2OTs-piperidine
EINECS	Contact for details

Quality Control

Our 4-Cyano-4-(Toluene-4-Sulfonyloxymethyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.