Description

6-Amino-2,3-Dihydro-Benzo[1,4]Oxazine-4-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its benzoxazine core structure and protected carboxylic acid group. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), offering a versatile scaffold for medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical manufacturers developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Used in the multi-step synthesis of complex active pharmaceutical ingredients (APIs) requiring a functionalized benzoxazine moiety.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.
• Organic Synthesis Building Block: Utilized in academic and industrial research for constructing heterocyclic compounds and exploring new chemical reactions.

Basic Information

Product Name	6-Amino-2,3-Dihydro-Benzo[1,4]Oxazine-4-Carboxylic Acid tert-Butyl Ester
CAS No.	928118-00-7
Molecular Formula	C13H18N2O3
Molecular Weight	250.29 g/mol
Synonyms	tert-Butyl 6-amino-2,3-dihydro-4H-1,4-benzoxazine-4-carboxylate; 6-Amino-3,4-dihydro-2H-1,4-benzoxazine-4-carboxylic acid tert-butyl ester; 2H-1,4-Benzoxazine-4-carboxylic acid, 6-amino-3,4-dihydro-, 1,1-dimethylethyl ester; 6-Amino-2,3-dihydro-1,4-benzoxazine-4-carboxylic acid tert-butyl ester; 4H-1,4-Benzoxazine-4-carboxylic acid, 6-amino-3,4-dihydro-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 6-Amino-2,3-Dihydro-Benzo[1,4]Oxazine-4-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.